About the Authors

Katrina M. Burchett

Affiliation Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Ying Yan

Affiliation Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Michel M. Ouellette

mouellet@unmc.edu

Affiliations Eppley Institute for Research in Cancer, University of Nebraska Medical Center, Omaha, Nebraska, United States of America, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Competing Interests

The authors have the following interests. GRN163L and the mismatched oligo were provided free of charge by Geron Corp. (Menlo Park, CA). The authors wish to express their gratitude for the advice, feedback and additional reagents provided to them by Sergei Gryaznov, Robert Tressler, Ning Go and Katia Bassett from Geron Corp. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YY MMO. Performed the experiments: KMB YY. Analyzed the data: KMB YY MMO. Contributed reagents/materials/analysis tools: YY MMO. Wrote the paper: YY MMO.