About the Authors

Pietro Guaraldi

pietro.guaraldi@unibo.it

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Roberto Poda

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Giovanna Calandra-Buonaura

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Laura Solieri

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Luisa Sambati

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Roberto Gallassi

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Pietro Cortelli

Affiliations IRCCS, Institute of Neurological Sciences of Bologna, Bologna, Italy, Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy

Competing Interests

PG reports no competing interests. RP reports no competing interests. GCB has received honoraria for speaking engagements from Lundbeck (Italia) and UCB Pharma S.p.A. L.Solieri has received honoraria for experimental study participation by Chelsea Therapeutics. L.Sambati reports no competing interests. RG reports no competing interests. PC has received honoraria for speaking engagements or consulting activities with Allergan (Italia), Boehringer Ingelheim (Italia), Chelsea Therapeutics, GlaxoSmithKline S.p.A, Lundbeck (Italia), Merck Sharp & Dohme (Italia), Teva, UCB Pharma S.p.A, Chiesi Farmaceutici and AbbVie srl. This does not alter the authors′ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RG PC. Performed the experiments: PG RP GCB L. Sambati L. Solieri. Analyzed the data: PG RP GCB. Contributed reagents/materials/analysis tools: PG RP L. Sambati L. Solieri Wrote the paper: PG RP GCB L. Sambati RG PC.