About the Authors

Maria Chiara Barsotti

Contributed equally to this work with: Maria Chiara Barsotti, Paola Losi

mariachiara1970@yahoo.it

Affiliation Department of Surgery, Medical, Molecular, and Critical Area Pathology, University of Pisa, Pisa, Italy

Paola Losi

Contributed equally to this work with: Maria Chiara Barsotti, Paola Losi

Affiliation Institute of Clinical Physiology, National Research Council, Massa, Italy

Enrica Briganti

Affiliation Institute of Clinical Physiology, National Research Council, Massa, Italy

Elena Sanguinetti

Affiliation Institute of Clinical Physiology, National Research Council, Massa, Italy

Angela Magera

Affiliation Kedrion SpA, Castelvecchio Pascoli, Italy

Tamer Al Kayal

Affiliation Institute of Clinical Physiology, National Research Council, Massa, Italy

Roberto Feriani

Affiliation Department of Surgery, Medical, Molecular, and Critical Area Pathology, University of Pisa, Pisa, Italy

Rossella Di Stefano

Affiliation Department of Surgery, Medical, Molecular, and Critical Area Pathology, University of Pisa, Pisa, Italy

Giorgio Soldani

Affiliation Institute of Clinical Physiology, National Research Council, Massa, Italy

Competing Interests

The authors declare that one of the authors, Dr. Angela Magera, who performed growth factor quantification in platelet lysate, is an employee of KEDRION S.p.A, which was involved in this study by a Research Agreement (BANDO UNICO R&D Regional Program 2008 "Nanostructured materials based on fibrin and platelet factors for angiogenesis promotion", funded by Regione Toscana). This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MCB PL EB RDS GS. Performed the experiments: MCB PL EB ES AM TAK RF. Analyzed the data: MCB PL EB TAK RF. Wrote the manuscript: MCB PL EB ES AM TAK RF RDS GS.