About the Authors

Ira M. Mostovaya

I.M.Mostovaya@umcutrecht.nl

Affiliation Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands

Michiel L. Bots

Affiliation Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands

Marinus A. van den Dorpel

Affiliation Department of Internal Medicine, Maasstad Hospital, Rotterdam, the Netherlands

Roel Goldschmeding

Affiliation Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands

Claire H. den Hoedt

Affiliations Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Internal Medicine, Maasstad Hospital, Rotterdam, the Netherlands

Otto Kamp

Affiliation Department of Cardiology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Renée Levesque

Affiliation Department of Nephrology, Centre Hospitalier de l'Université de Montréal St. Luc Hospital, Montréal, Canada

Albert H. A. Mazairac

Affiliation Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands

E. Lars Penne

Affiliations Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Nephrology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Dorine W. Swinkels

Affiliation Department of Laboratory Medicine, Laboratory of Genetic, Endocrine and Metabolic diseases, Radboud University Medical Centre Nijmegen, the Netherlands

Neelke C. van der Weerd

Affiliations Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands, Department of Nephrology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Piet M. ter Wee

Affiliations Department of Nephrology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands, Institute for Cardiovascular Research Vrije Universiteit Medical Center, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Menso J. Nubé

Affiliations Department of Nephrology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands, Institute for Cardiovascular Research Vrije Universiteit Medical Center, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Peter J. Blankestijn

Affiliation Department of Nephrology, University Medical Center Utrecht, Utrecht, the Netherlands

Muriel P. C. Grooteman

Affiliations Department of Nephrology, Vrije Universiteit Medical Center, Amsterdam, the Netherlands, Institute for Cardiovascular Research Vrije Universiteit Medical Center, Vrije Universiteit Medical Center, Amsterdam, the Netherlands

Competing Interests

The authors have the following interests: CONTRAST is partly supported by unrestricted grants from Fresenius Medical Care (The Netherlands) and Gambro Lundia AB (Sweden). Additional support for CONTRAST was also received from Roche, the Netherlands. There are no patents, products in development or marketed products to declare. IM Mostovaya, CH den Hoedt, O Kamp, ML Bots, NC van der Weerd, EL Penne, and AHA Mazairac report receiving no lecture fees, no consulting support, or grant support. MPC Grooteman reports research funded by Fresenius, Gambro, and Baxter. PJ Blankestijn reports research funded by Fresenius, Gambro, Roche, Amgen, and Novartis; consultant fee and honoraria for lectures from Fresenius, Gambro, Solvay, Medtronic, and Novartis. R Lévesque reports research funded by Amgen Canada. PM ter Wee reports research funded by Abbott, Baxter, Gambro, Fresenius, and Roche; honoraria for lectures received from Amgen, Roche, Genzyme, Fresenius. MJ Nubé reports research funded by Baxter and Fresenius; honoraria for lectures received from Fresenius and Baxter. MA van den Dorpel reports research funded by Amgen. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MB MD PW MN PB MG RL. Performed the experiments: MB MD PW MN PB MG CH AM NW LP RL. Analyzed the data: IM MB. Contributed reagents/materials/analysis tools: RG DS OK. Wrote the paper: IM MB PB.