About the Authors

Isabelle Sermadiras

sermadirasi@medimmune.com

Affiliation Antibody Discovery and Protein Engineering, Research, MedImmune, Cambridge, United Kingdom

Jefferson Revell

Affiliation Antibody Discovery and Protein Engineering, Research, MedImmune, Cambridge, United Kingdom

John E. Linley

Affiliation Neuroscience in vitro Biology, Research, MedImmune, Cambridge, United Kingdom

Alan Sandercock

Affiliation Antibody Discovery and Protein Engineering, Research, MedImmune, Cambridge, United Kingdom

Peter Ravn

Affiliation Antibody Discovery and Protein Engineering, Research, MedImmune, Cambridge, United Kingdom

Competing Interests

At the time when the work for this manuscript was performed, all authors were employed by MedImmune and held stock in MedImmune, Ltd. All the authors were involved in study design, data collection and analysis, decision to publish and preparation of the manuscript. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: IS PR. Performed the experiments: IS JR JL AS. Analyzed the data: IS JL AS PR. Contributed reagents/materials/analysis tools: IS JR JL AS. Wrote the manuscript: IS PR.