About the Authors

Jennifer H. Cox

Affiliation Department of Cellular Immunology, Novo Nordisk Research Center, Seattle, Washington, United States of America

Scott Hussell

Affiliation Department of Cellular Immunology, Novo Nordisk Research Center, Seattle, Washington, United States of America

Henrik Søndergaard

Affiliation Department of Immunopharmacology, Novo Nordisk A/S, Maløv, Denmark

Kirstine Roepstorff

Affiliation Department of Histology, Novo Nordisk A/S, Maløv, Denmark

John-Vu Bui

Affiliation Department of Cellular Immunology, Novo Nordisk Research Center, Seattle, Washington, United States of America

Jen Running Deer

Affiliation Department of Molecular Immunology, Novo Nordisk Research Center, Seattle, Washington, United States of America

Jun Zhang

Affiliation Department of Cell Biology, Beijing Novo Nordisk Pharmaceuticals Science & Technology Co., Beijing, China

Zhan-Guo Li

Affiliation Department of Rheumatology & Immunology, Beijing University People’s Hospital, Beijing, China

Kasper Lamberth

Affiliation Department of Screening and Cell Technology, Novo Nordisk A/S, Maløv, Denmark

Peter Helding Kvist

Affiliation Department of Histology, Novo Nordisk A/S, Maløv, Denmark

Søren Padkjær

Affiliation Department of Protein Structure and Biophysics, Novo Nordisk A/S, Maløv, Denmark

Claus Haase

Affiliation Department of Immunopharmacology, Novo Nordisk A/S, Maløv, Denmark

Stefan Zahn

Affiliation Department of Antibody Technology, Novo Nordisk A/S, Maløv, Denmark

Valerie H. Odegard

VALO@novonordisk.com

Affiliation Department of Cellular Immunology, Novo Nordisk Research Center, Seattle, Washington, United States of America

Competing Interests

Funding was received from Novo Nordisk, a commercial source, and all authors are current employees or collaborators of Novo Nordisk and have no additional conflicting financial interests. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JHC SH HS KR JVB JZ KL JRD PHK CH SZ VHO. Performed the experiments: JHC SH HS KR JVB JZ KL PHK CH SZ. Analyzed the data: JHC SH HS KR JVB JZ JRD KL PHK SP CH SZ. Contributed reagents/materials/analysis tools: ZGL. Wrote the paper: JHC HS VDO.