About the Authors

Laura Pasin

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Teresa Greco

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Paolo Feltracco

Affiliation Department of Pharmacology and Anesthesiology, University Hospital of Padua, Padua, Italy

Annalisa Vittorio

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Caetano Nigro Neto

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Luca Cabrini

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Giovanni Landoni

landoni.giovanni@hsr.it

Affiliations Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy, Outcomes Research Consortium, Cleveland, Ohio, United States of America

Gabriele Finco

Affiliation Department of Medical Sciences “M. Aresu”, Cagliari University, Cagliari, Italy

Alberto Zangrillo

Affiliation Anesthesia and Intensive Care Department, San Raffaele Scientific Institute, Milan, Italy

Competing Interests

Giovanni Landoni is a PLOS ONE Editorial Board member. This does not alter the authors adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: LP TG PF AV CNN LC GL GF AZ. Performed the experiments: LP TG PF AV CNN LC GL GF AZ. Analyzed the data: LP TG PF AV CNN LC GL GF AZ. Contributed reagents/materials/analysis tools: LP TG PF AV CNN LC GL GF AZ. Wrote the paper: LP TG PF AV CNN LC GL GF AZ.