About the Authors

Izumi Fukumoto

Affiliation Fixed Prosthodontics, Department of Restorative Sciences, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

Atsushi Tamura

tamura.org@tmd.ac.jp

Affiliation Department of Organic Biomaterials, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

Mitsuaki Matsumura

Affiliation Fixed Prosthodontics, Department of Restorative Sciences, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

Hiroyuki Miura

Affiliation Fixed Prosthodontics, Department of Restorative Sciences, Division of Oral Health Sciences, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan

Nobuhiko Yui

Affiliation Department of Organic Biomaterials, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Tokyo, Japan

Competing Interests

The authors have read the journal’s policy and have the following conflicts: part of this work was financially supported by a Torii Pharmaceutical. There is no employment, consultancy, patents, or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: IF AT MM HM NY. Performed the experiments: IF AT. Analyzed the data: IF AT MM HM NY. Contributed reagents/materials/analysis tools: AT NY. Wrote the manuscript: IF AT MM HM NY.