About the Authors

Maki Tsumura

Affiliation Department of Physiology, Tokyo Dental College, Chiba, Japan

Ubaidus Sobhan

Affiliations Department of Physiology, Tokyo Dental College, Chiba, Japan, Clinical Research Center, National Center for Child Health and Development, Tokyo, Japan

Masaki Sato

Affiliation Department of Physiology, Tokyo Dental College, Chiba, Japan

Miyuki Shimada

Affiliation Department of Clinical Oral Health Science, Tokyo Dental College, Tokyo, Japan

Akihiro Nishiyama

Affiliation Department of Oral Medicine, Oral and Maxillofacial Surgery, Tokyo Dental College, Chiba, Japan

Aya Kawaguchi

Affiliation Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan

Manabu Soya

Affiliation Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan

Hidetaka Kuroda

Affiliation Department of Anesthesiology and Pain Relief Center, University of Tokyo Hospital, Tokyo, Japan

Masakazu Tazaki

Affiliation Department of Physiology, Tokyo Dental College, Chiba, Japan

Yoshiyuki Shibukawa

yshibuka@tdc.ac.jp

Affiliation Department of Physiology, Tokyo Dental College, Chiba, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: M. Tsumura M. Tazaki YS. Performed the experiments: M. Tsumura US M. Sato M. Shimada AN AK M. Soya HK. Analyzed the data: M. Tsumura US M. Sato M. Shimada AN AK M. Soya HK YS. Wrote the paper: M. Tsumura YS.