About the Authors

Laura De Lellis

Affiliation Department of Pharmacy, “G. d’Annunzio” University, Chieti, Italy

Gitana Maria Aceto

Affiliations Department of Experimental and Clinical Sciences, “G. d’Annunzio” University, Chieti, Italy, Unit of Molecular Pathology and Genomics, Aging Research Center, “G. d’Annunzio” University Foundation, Chieti, Italy

Maria Cristina Curia

Affiliations Department of Medical, Oral and Biotechnological Sciences, “G. d’Annunzio” University, Chieti, Italy, Unit of Molecular Pathology and Genomics, Aging Research Center, “G. d’Annunzio” University Foundation, Chieti, Italy

Teresa Catalano

Affiliation Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy

Sandra Mammarella

Affiliation Department of Pharmacy, “G. d’Annunzio” University, Chieti, Italy

Serena Veschi

Affiliation Unit of Molecular Pathology and Genomics, Aging Research Center, “G. d’Annunzio” University Foundation, Chieti, Italy

Fabiana Fantini

Affiliation Department of Experimental and Clinical Sciences, “G. d’Annunzio” University, Chieti, Italy

Pasquale Battista

Affiliation Department of Experimental and Clinical Sciences, “G. d’Annunzio” University, Chieti, Italy

Vittoria Stigliano

Affiliation Department of Gastroenterology, Unit of Hereditary Colorectal Cancer, National Cancer Institute, Regina Elena (IRE), Rome, Italy

Luca Messerini

Affiliation Section of Pathological Anatomy, Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy

Cristina Mareni

Affiliation Department of Internal Medicine, University of Genova, Genova, Italy

Paola Sala

Affiliation Unit of Hereditary Digestive Tract Tumors, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

Lucio Bertario

Affiliation Unit of Hereditary Digestive Tract Tumors, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

Paolo Radice

Affiliation Unit of Molecular bases of genetic risk and genetic testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy

Alessandro Cama

cama@unich.it

Affiliation Department of Pharmacy, “G. d’Annunzio” University, Chieti, Italy

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AC. Performed the experiments: LDL GMA MCC TC SM SV FF. Analyzed the data: LDL GMA MCC TC SM SV FF PR AC. Contributed reagents/materials/analysis tools: PB VS LM CM PS LB PR AC. Wrote the manuscript: LDL AC. Recruitment of patients: VS LM CM PS LB PR. Critical revision of the manuscript: LB PR.