About the Authors

Maxime Culot

Contributed equally to this work with: Maxime Culot, Anaëlle Fabulas - da Costa

maxime.culot@univ-artois.fr

Affiliation BBB Laboratory EA 2465, IMPRT: IFR114 Université Lille Nord de France, UArtois, Lens, France

Anaëlle Fabulas - da Costa

Contributed equally to this work with: Maxime Culot, Anaëlle Fabulas - da Costa

Affiliation BBB Laboratory EA 2465, IMPRT: IFR114 Université Lille Nord de France, UArtois, Lens, France

Emmanuel Sevin

Affiliation BBB Laboratory EA 2465, IMPRT: IFR114 Université Lille Nord de France, UArtois, Lens, France

Erica Szorath

Affiliation DMPK department, AstraZeneca R&D, Södertälje, Sweden

Stefan Martinsson

Affiliation DMPK department, AstraZeneca R&D, Södertälje, Sweden

Mila Renftel

Affiliation DMPK department, AstraZeneca R&D, Södertälje, Sweden

Yan Hongmei

Affiliation DMPK department, AstraZeneca R&D, Södertälje, Sweden

Romeo Cecchelli

Affiliation BBB Laboratory EA 2465, IMPRT: IFR114 Université Lille Nord de France, UArtois, Lens, France

Stefan Lundquist

Affiliation DMPK department, AstraZeneca R&D, Södertälje, Sweden

Competing Interests

This study was partly funded by AstraZeneca R&D, the employer of Erica Szorath, Stefan Martinsson, Mila Renftel, Yan Hongmei and Stefan Lundquist. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MC SL. Performed the experiments: AD E. Sevin E. Szorath SM MR YH. Analyzed the data: MC AD E. Sevin SL. Contributed reagents/materials/analysis tools: SL RC. Wrote the paper: MC AD E. Sevin RC SL.