About the Authors

Xia Liu

Contributed equally to this work with: Xia Liu, Wei Zhu

Affiliation Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Wei Zhu

Contributed equally to this work with: Xia Liu, Wei Zhu

Affiliation Naval Medical Research Institute, Shanghai, China

Shuhong Guan

Affiliation National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Ruihong Feng

Affiliation National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Hui Zhang

Affiliation Naval Medical Research Institute, Shanghai, China

Qiuhong Liu

Affiliation Naval Medical Research Institute, Shanghai, China

Peng Sun

Affiliation Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Donghai Lin

zhu_wei2002@163.com (JS); nxzhang@mail.shcnc.ac.cn (NZ); dhlin@xmu.edu.cn (DL)

Affiliation Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China

Naixia Zhang

zhu_wei2002@163.com (JS); nxzhang@mail.shcnc.ac.cn (NZ); dhlin@xmu.edu.cn (DL)

Affiliation Department of Analytical Chemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Jun Shen

zhu_wei2002@163.com (JS); nxzhang@mail.shcnc.ac.cn (NZ); dhlin@xmu.edu.cn (DL)

Affiliation Naval Medical Research Institute, Shanghai, China

Competing Interests

The TCM formula (FJJOL) referred in this article had been patented with anti-anxiety effects, and the name of the patent is “an anti-anxiety TCM formula and its preparation method”. The patent was licensed and issued by the China Intellectual Property Office (Chinese patent No. ZL20101060604032.4). Below is the authors’ declarations related to the patent. (1) The patent belongs to Naval Medical Research Institute, and due to this crucial contribution, the authors rank Naval Medical Research Institute as the first communication unit of this article. (2) The inventors of the patent are Wei Zhu, Chong-Ming Xu, Jun Shen, Hui Zhang, and Qiu-hong Liu. Except Chong-Ming Xu, who has not contributed to the research work reported in this article, all the other involved inventors are on the author list. (3) Since the patent has been licensed and could be accessed by the public, all the related information provided in this article will not cause any conflict of interest.

Author Contributions

Conceived and designed the experiments: XL WZ NZ. Performed the experiments: XL WZ SG RF HZ QL PS. Analyzed the data: XL WZ SG RF. Contributed reagents/materials/analysis tools: XL WZ SG RF HZ QL PS DL NZ JS. Wrote the manuscript: XL NZ.