MicroRNA-34a Enhances T Cell Activation by Targeting Diacylglycerol Kinase ζ

Jinwook Shin; Danli Xie; Xiao-Ping Zhong

doi:10.1371/journal.pone.0077983

Loading metrics

Open Access

Peer-reviewed

Research Article

MicroRNA-34a Enhances T Cell Activation by Targeting Diacylglycerol Kinase ζ

Jinwook Shin,

Affiliation Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯
Danli Xie,

Affiliations Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Xiao-Ping Zhong

* E-mail: zhong001@mc.duke.edu

Affiliations Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America
⨯

MicroRNA-34a Enhances T Cell Activation by Targeting Diacylglycerol Kinase ζ

Jinwook Shin,
Danli Xie,
Xiao-Ping Zhong

Published: October 17, 2013
https://doi.org/10.1371/journal.pone.0077983

About the Authors

Jinwook Shin

Affiliation Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

Danli Xie

Affiliations Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, School of Laboratory Medicine, Wenzhou Medical University, Wenzhou, Zhejiang, China

Xiao-Ping Zhong

* E-mail: zhong001@mc.duke.edu

Affiliations Department of Pediatrics, Division of Allergy and Immunology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Immunology, Duke University Medical Center, Durham, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JS XPZ. Performed the experiments: JS DX. Analyzed the data: JS DX. Wrote the manuscript: JS XPZ.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
3' UTR
Is the Subject Area "3' UTR" applicable to this article?

Thanks for your feedback.
T cell receptors
Is the Subject Area "T cell receptors" applicable to this article?

Thanks for your feedback.
293T cells
Is the Subject Area "293T cells" applicable to this article?

Thanks for your feedback.
Messenger RNA
Is the Subject Area "Messenger RNA" applicable to this article?

Thanks for your feedback.
Phosphorylation
Is the Subject Area "Phosphorylation" applicable to this article?

Thanks for your feedback.
TCR signaling cascade
Is the Subject Area "TCR signaling cascade" applicable to this article?

Thanks for your feedback.