About the Authors

Seiichi Sato

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Yingshe Zhao

Affiliation Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America

Misa Imai

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Philip C. Simister

Affiliation Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

Stephan M. Feller

Affiliations Department of Oncology, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom, Section Tumor Biology, Institute of Molecular Medicine, Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany

Philip C. Trackman

Affiliation Division of Oral Biology, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, United States of America

Kathrin H. Kirsch

Affiliation Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts, United States of America

Gail E. Sonenshein

gail.sonenshein@tufts.edu

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Competing Interests

The authors would like to acknowledge that co-author Philip C. Trackman is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SS PCS SMF PCT KHK GES. Performed the experiments: SS YZ MI PCS. Analyzed the data: SS YZ MI PCS SMF PCT KHK GES. Contributed reagents/materials/analysis tools: PCT. Wrote the paper: SS YZ MI PCS SMF PCT KHK GES.