About the Authors

Xin Ma

Affiliation Department of Statistics, Stanford University, Stanford, California, United States of America

Joanna L. Kelley

Affiliation Department of Genetics, Stanford University, Stanford, California, United States of America

Kirsten Eilertson

Affiliation Bioinformatics Core, Gladstone Institutes, San Francisco, California, United States of America

Shaila Musharoff

Affiliation Department of Genetics, Stanford University, Stanford, California, United States of America

Jeremiah D. Degenhardt

Current address: Onyx Pharmaceuticals, South San Francisco, California, United States of America

Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

André L. Martins

Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Tomas Vinar

Affiliation Department of Applied Informatics, Comenius University, Bratislava, Slovakia

Carolin Kosiol

Affiliation Institute of Population Genetics, Vetmeduni Vienna, Vienna, Austria

Adam Siepel

Affiliation Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America

Ryan N. Gutenkunst

Affiliation Department of Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, United States of America

Carlos D. Bustamante

cdbustam@stanford.edu

Affiliation Department of Genetics, Stanford University, Stanford, California, United States of America

Competing Interests

CDB is on the Scientific or Medical Advsiory Board of several companies including Personalis, Inc., InVitae, and Ancestry.com. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Analyzed the data: XM JLK SM JDD ALM RNG. Contributed reagents/materials/analysis tools: XM KE TV CK AS RNG. Wrote the paper: XM JLK RNG JDD SM CDB. Conceived and directed the project: XM CDB.