About the Authors

Robert Tsanev

robert.tsanev@ttu.ee

Affiliation Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

Kalju Vanatalu

Affiliation Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

Jüri Jarvet

Affiliation National Institute of Chemical Physics and Biophysics, Tallinn, Estonia

Risto Tanner

Affiliation National Institute of Chemical Physics and Biophysics, Tallinn, Estonia

Kristi Laur

Affiliation Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

Piret Tiigimägi

Affiliation Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

Birthe B. Kragelund

Affiliation Structural Biology and Nuclear Magnetic Resonance Laboratory, University of Copenhagen, Copenhagen, Denmark

Torben Østerlund

Affiliation Molecular Pharmacology, Zealand Pharma A/S, Glostrup, Denmark

Priit Kogerman

Affiliation Department of Gene Technology, Tallinn University of Technology, Tallinn, Estonia

Competing Interests

Torben Østerlund is employed by a commercial company, Zealand Pharma A/S. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: R. Tsanev KV JJ KL PT BK TØ PK. Performed the experiments: R. Tsanev KV JJ R. Tanner KL PT. Analyzed the data: R. Tsanev KV JJ KL PT BK TØ PK. Contributed reagents/materials/analysis tools: KV JJ R. Tanner BK TØ PK. Wrote the paper: R. Tsanev KV JJ R. Tanner KL BK TØ.