About the Authors

Marta Solinas

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Paola Massi

Affiliation Department of Pharmacology, Chemotherapy and Toxicology, University of Milan, Milan, Italy

Valentina Cinquina

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Marta Valenti

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Daniele Bolognini

Affiliation Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada

Marzia Gariboldi

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Elena Monti

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Tiziana Rubino

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Daniela Parolaro

daniela.parolaro@uninsubria.it

Affiliation Department of Theoretical and Applied Sciences, Biomedical Research Division, Centre of Neuroscience, University of Insubria, Busto Arsizio, Varese, Italy

Competing Interests

GW Pharmaceuticals funded part of the research. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MS PM MV DB MG EM DP. Performed the experiments: MS VC MV DB MG. Analyzed the data: MS VC MV DB MG. Wrote the paper: MS PM MV MG EM TR DP.