About the Authors

Sofia B. Carvalho

Affiliation Instituto Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Hugo M. Botelho

Current address: Center for Biodiversity, Functional and Integrative Genomics, Faculty of Sciences, University of Lisboa, Lisboa, Portugal

Affiliation Instituto Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Sónia S. Leal

Affiliation Instituto Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Isabel Cardoso

Affiliations Molecular Neurobiology Unit, Instituto de Biologia Molecular e Celular, Porto, Portugal, Escola Superior Tecnologia Saúde Porto, Instituto Politécnico, Porto, Vila Nova de Gaia, Portugal

Günter Fritz

Affiliation Department of Neuropathology, University of Freiburg, Freiburg, Germany

Cláudio M. Gomes

gomes@itqb.unl.pt

Affiliation Instituto Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal

Competing Interests

Co-author Cláudio Gomes is a PLOS ONE Editorial Board member, and this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CMG SBC HMB SL. Performed the experiments: SBC HMB SL IC. Analyzed the data: CMG SBC HMB SL IC GF. Contributed reagents/materials/analysis tools: GF IC. Wrote the manuscript: CMG GF SBC SL IC HB.