About the Authors

Kelly Devereaux

Affiliations Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, New York, United States of America

Claudia Dall’Armi

Contributed equally to this work with: Claudia Dall’Armi, Abel Alcazar-Roman

Affiliations Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, New York, United States of America

Abel Alcazar-Roman

Contributed equally to this work with: Claudia Dall’Armi, Abel Alcazar-Roman

Affiliations Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Yuta Ogasawara

Affiliation Department of Animal Bio-Science, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan

Xiang Zhou

Affiliations Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States of America

Fan Wang

Affiliations Department of Cell Biology, Duke University Medical Center, Durham, North Carolina, United States of America, Department of Neurobiology, Duke University Medical Center, Durham, North Carolina, United States of America

Akitsugu Yamamoto

Affiliation Department of Animal Bio-Science, Faculty of Bio-Science, Nagahama Institute of Bio-Science and Technology, Nagahama, Shiga, Japan

Pietro De Camilli

Affiliations Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut, United States of America

Gilbert Di Paolo

gil.dipaolo@columbia.edu

Affiliations Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, United States of America, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KAD CDA AAR AY PDC GDP. Performed the experiments: KAD CDA AAR YO XZ AY. Analyzed the data: KAD CDA AAR YO AY GDP. Contributed reagents/materials/analysis tools: KAD AAR YO XZ FW AY PDC GDP. Wrote the manuscript: KAD GDP.