About the Authors

Hiroshi Kobayashi

Affiliations Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan, Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan, Department of Oral and Maxillofacial Surgery, Nagano Matsushiro General Hospital, Nagano, Japan

Kenichi Kumagai

Contributed equally to this work with: Kenichi Kumagai, Ryuji Suzuki

Affiliations Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan, Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan

Takanori Eguchi

Affiliations Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan, Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan, Department of Oral and Maxillofacial Surgery, Toshiba Rinkan Hospital, Sagamihara, Japan

Hiroaki Shigematsu

Affiliations Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan, Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan

Kazutaka Kitaura

Affiliation Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan

Mitsuko Kawano

Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan

Tatsuya Horikawa

Affiliation Department of Dermatology, Nishi-Kobe Medical Center, Kobe, Japan

Satsuki Suzuki

Affiliation Section of Biological Science, Research Center for Odontology, Nippon Dental University, Tokyo, Japan

Takaji Matsutani

Affiliation Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan

Kouetsu Ogasawara

Affiliation Department of Immunobiology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan

Yoshiki Hamada

Affiliation Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan

Ryuji Suzuki

Contributed equally to this work with: Kenichi Kumagai, Ryuji Suzuki

r-suzuki@sagamihara-hosp.gr.jp

Affiliation Department of Rheumatology and Clinical Immunology, Clinical Research Center for Rheumatology and Allergy, Sagamihara National Hospital, National Hospital Organization, Sagamihara, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: K. Kumagai TH SS KO RS. Performed the experiments: HK TE HS K. Kitaura. Analyzed the data: HK. Contributed reagents/materials/analysis tools: TE HS K. Kitaura MK. Wrote the manuscript: K. Kumagai HK TM. Coordinated the study as the principal investigator: RS YH KO.