Attenuation of Chondrogenic Transformation in Vascular Smooth Muscle by Dietary Quercetin in the MGP-Deficient Mouse Model

Kelly E. Beazley; Florence Lima; Teresa Borras; Maria Nurminskaya

doi:10.1371/journal.pone.0076210

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Peer-reviewed

Research Article

Attenuation of Chondrogenic Transformation in Vascular Smooth Muscle by Dietary Quercetin in the MGP-Deficient Mouse Model

Kelly E. Beazley ,

Contributed equally to this work with: Kelly E. Beazley, Florence Lima

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
⨯
Florence Lima ,

Contributed equally to this work with: Kelly E. Beazley, Florence Lima

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
⨯
Teresa Borras,

Affiliation Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America
⨯
Maria Nurminskaya

* E-mail: mnurminskaya@som.umaryland.edu

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America
⨯

Attenuation of Chondrogenic Transformation in Vascular Smooth Muscle by Dietary Quercetin in the MGP-Deficient Mouse Model

Kelly E. Beazley,
Florence Lima,
Teresa Borras,
Maria Nurminskaya

Published: September 30, 2013
https://doi.org/10.1371/journal.pone.0076210

About the Authors

Kelly E. Beazley

Contributed equally to this work with: Kelly E. Beazley, Florence Lima

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

Florence Lima

Contributed equally to this work with: Kelly E. Beazley, Florence Lima

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

Teresa Borras

Affiliation Department of Ophthalmology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina, United States of America

Maria Nurminskaya

* E-mail: mnurminskaya@som.umaryland.edu

Affiliation Department of Biochemistry and Molecular Biology, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KB FL TB MN. Performed the experiments: KB FL. Analyzed the data: KB FL. Contributed reagents/materials/analysis tools: KB FL TB MN. Wrote the manuscript: KB MN.

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Beta-catenin signaling
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Cartilage
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Calcification
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Signal inhibition
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Collagens
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Diet
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Aorta
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Transcription factors
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