About the Authors

Debra A. Schaumberg

debra.schaumberg@utah.edu

Affiliations Division of Preventive Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Ophthalmology & Visual Sciences, Center for Translational Medicine, John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Schepens Eye Research Institute, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Miki Uchino

Affiliation Department of Ophthalmology, School of Medicine, Keio University, Tokyo, Japan

William G. Christen

Affiliation Division of Preventive Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Richard D. Semba

Affiliations Division of Preventive Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Julie E. Buring

Affiliations Division of Preventive Medicine, Brigham & Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

Jim Z. Li

Affiliation Global Outcomes Research, Pfizer, Inc., San Diego, California, United States of America

Competing Interests

This study was partly funded by Pfizer, the employer of Jim Z. Li. Dr. Li held equity interest in Pfizer, Inc. Dr. Schaumberg was a periodic consultant for Pfizer, Inc. (on other topics not overlapping with the submitted work), as well as Alcon, Eleven Biotherapeutics, Inspire Pharmaceuticals, and Allergan, Inc.; and held equity interest in TearLab, Inc. and Mimetogen Pharmaceuticals. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: DAS. Performed the experiments: DAS WGC JEB. Analyzed the data: DAS. Contributed reagents/materials/analysis tools: DAS WGC RDS JEB JZL. Wrote the manuscript: DAS MU JZL.