A Loss-Of-Function Analysis Reveals That Endogenous Rem2 Promotes Functional Glutamatergic Synapse Formation and Restricts Dendritic Complexity

Anna R. Moore; Amy E. Ghiretti; Suzanne Paradis

doi:10.1371/journal.pone.0074751

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Peer-reviewed

Research Article

A Loss-Of-Function Analysis Reveals That Endogenous Rem2 Promotes Functional Glutamatergic Synapse Formation and Restricts Dendritic Complexity

Anna R. Moore,

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America
⨯
Amy E. Ghiretti,

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America
⨯
Suzanne Paradis

* E-mail: paradis@brandeis.edu

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America
⨯

A Loss-Of-Function Analysis Reveals That Endogenous Rem2 Promotes Functional Glutamatergic Synapse Formation and Restricts Dendritic Complexity

Anna R. Moore,
Amy E. Ghiretti,
Suzanne Paradis

Published: August 26, 2013
https://doi.org/10.1371/journal.pone.0074751

About the Authors

Anna R. Moore

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America

Amy E. Ghiretti

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America

Suzanne Paradis

* E-mail: paradis@brandeis.edu

Affiliation Department of Biology, National Center for Behavioral Genomics and Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ARM AEG SP. Performed the experiments: ARM AEG. Analyzed the data: ARM AEG. Wrote the manuscript: ARM AEG SP.

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RNA interference
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Neuronal dendrites
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Synapses
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