About the Authors

Herta H. Chao

herta.chao@yale.edu

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

Sien Hu

Affiliation Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America

Jaime S. Ide

Affiliation Department of Science and Technology, Federal University of Sao Paolo, Salo Paolo, Brazil

Edward Uchio

Affiliation Tower Research, Los Angeles, California, United States of America

Sheng Zhang

Affiliation Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America

Michal Rose

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

John Concato

Affiliations Department of Internal Medicine & Yale Comprehensive Cancer Center, Yale University School of Medicine, New Haven, Connecticut, United States of America, Medical Service, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America, Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, Connecticut, United States of America

Chiang-shan R. Li

Affiliations Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, United States of America, Deparment of Neurobiology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Interdepartmental Neuroscience Program, Yale University, New Haven, Connecticut, United States of America

Competing Interests

Dr. Edward Uchio who participated in this study as an employee of the Department of Veterans Affairs/US government is currently employed by a private company, Tower Research, Los Angeles, CA. The authors confirm that there are no competing interests as a result of the current employment and that this does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: HHC EU MR JC C-SRL. Performed the experiments: HHC SH EU. Analyzed the data: JI SZ C-SRL. Wrote the paper: HHC MR JC C-SRL. Read and approved the final manuscript: HHC SH JI EU SZ MR JC C-SRL.