About the Authors
- Thomas A. Munro
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* E-mail: thomas@munro.com
Affiliations McLean Hospital, Belmont, Massachusetts, United States of America, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America, School of Chemistry and Bio21 Institute, University of Melbourne, Parkville, Australia
- Xi-Ping Huang
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Affiliation National Institute of Mental Health Psychoactive Drug Screening Program and Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
- Carmela Inglese
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Affiliation Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari, Bari, Italy
- Maria Grazia Perrone
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Affiliation Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari, Bari, Italy
- Ashlee Van't Veer
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Affiliations McLean Hospital, Belmont, Massachusetts, United States of America, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
- F. Ivy Carroll
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Affiliation Center for Organic and Medicinal Chemistry, Research Triangle Institute, Research Triangle Park, North Carolina, United States of America
- Cécile Béguin
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Affiliations McLean Hospital, Belmont, Massachusetts, United States of America, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
- William A. Carlezon Jr
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Affiliations McLean Hospital, Belmont, Massachusetts, United States of America, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
- Nicola A. Colabufo
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Affiliation Dipartimento di Farmacia-Scienze del Farmaco, Università degli Studi di Bari, Bari, Italy
- Bruce M. Cohen
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Affiliations McLean Hospital, Belmont, Massachusetts, United States of America, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
- Bryan L. Roth
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Affiliation National Institute of Mental Health Psychoactive Drug Screening Program and Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, United States of America
Competing Interests
The authors have read the journal's policy and have the following conflicts: CB, BMC, and WAC hold US patents on the use of κ ligands to treat mood disorders (6,528,518 and 7,629,475). RTI holds several US patents on the preparation and therapeutic use of JDTic, on which FIC is an author. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CB FIC WAC BMC NAC XPH CI MGP BLR AVV. Performed the experiments: XPH CI MGP NAC. Analyzed the data: XPH CI MGP NAC BLR. Contributed reagents/materials/analysis tools: FIC. Wrote the paper: TAM.