About the Authors

Uzoezi Ozomaro

Affiliations John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America, Department of Neuroscience, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Guiqing Cai

Contributed equally to this work with: Guiqing Cai, Yuji Kajiwara

Current address: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Affiliation Seaver Autism Center for Research and Treatment, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Yuji Kajiwara

Contributed equally to this work with: Guiqing Cai, Yuji Kajiwara

Affiliation Seaver Autism Center for Research and Treatment, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Seungtai Yoon

Affiliation Seaver Autism Center for Research and Treatment, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Vladimir Makarov

Current address: Department of Biostatistics, Mailman School of Public Health at Columbia University, New York, New York, United States of America

Affiliation Seaver Autism Center for Research and Treatment, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Richard Delorme

Affiliation Child Psychiatry Department, Robert Debré Hospital, Paris, France & Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France

Catalina Betancur

Affiliation Institut National de la Santé et de la Recherche Médicale U952, and Centre National de la Recherche Scientifique UMR 7224 and Université Pierre et Marie Curie, Paris, France

Stephan Ruhrmann

Affiliation Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany

Peter Falkai

Affiliation Department of Psychiatry and Psychotherapy, University of Homburg, Homburg, Germany

Hans Jörgen Grabe

Affiliation Department of Psychiatry and Psychotherapy, University of Greifswald, Stralsund, Germany

Wolfgang Maier

Affiliation Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany

Michael Wagner

Affiliation Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany

Leonhard Lennertz

Affiliation Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany

Rainald Moessner

Affiliation Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany

Dennis L. Murphy

Affiliation Laboratory of Clinical Science, National Institute of Mental Health Intramural Research Program, Bethesda, Maryland, United States of America

Joseph D. Buxbaum

Affiliation Seaver Autism Center for Research and Treatment, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Stephan Züchner

Affiliation John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

Dorothy E. Grice

Dorothy.grice@mssm.edu

Affiliation Division of Tics, Obsessive-Compulsive and Related Disorders, Department of Psychiatry, and the Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: UO GC YK JDB SZ DEG. Performed the experiments: UO GC YK. Analyzed the data: UO GC YK SY VM JDB SZ DEG. Contributed reagents/materials/analysis tools: SY VM RD CB SR PF HJG WM MW LL RM DLM. Wrote the paper: UO JDB SZ DEG. Final approval: UO GC YK SY VM RD CB SR PF HJG WM MW LL RM DLM JDB SZ DEG.