About the Authors

Wei-na Cong

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Rui Wang

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Huan Cai

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Caitlin M. Daimon

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Morten Scheibye-Knudsen

Affiliation Section on DNA repair, Laboratory of Molecular Gerontology, National Institute on Aging, Baltimore, Maryland, United States of America

Vilhelm A. Bohr

Affiliation Section on DNA repair, Laboratory of Molecular Gerontology, National Institute on Aging, Baltimore, Maryland, United States of America

Rebecca Turkin

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

William H. Wood III

Affiliation Gene Expression and Genomics Unit, Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, United States of America

Kevin G. Becker

Affiliation Gene Expression and Genomics Unit, Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, United States of America

Ruin Moaddel

Affiliation Bioanalytical Chemistry and Drug Discovery Section, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Stuart Maudsley

Contributed equally to this work with: Stuart Maudsley, Bronwen Martin

Affiliation Receptor Pharmacology Unit, Laboratory of Neurosciences, National Institute on Aging, Baltimore, Maryland, United States of America

Bronwen Martin

Contributed equally to this work with: Stuart Maudsley, Bronwen Martin

martinbro@mail.nih.gov

Affiliation Metabolism Unit, Laboratory of Clinical Investigation, National Institute on Aging, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WNC BM SM. Performed the experiments: WNC RW HC CMD MSK RT WHW RM. Analyzed the data: WNC RW HC MSK RM BM SM. Contributed reagents/materials/analysis tools: BM SM VAB KGB. Wrote the paper: WNC BM SM.