About the Authors

Jesse E. Hanson

jesseeh@gene.com

Affiliation Department of Neuroscience, Genentech, Inc. South San Francisco, California, United States of America

Hank La

Affiliation Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, United States of America

Emile Plise

Affiliation Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, United States of America

Yung-Hsiang Chen

Affiliation Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, United States of America

Xiao Ding

Affiliation Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, United States of America

Taleen Hanania

Affiliation PsychoGenics Inc., Tarrytown, New York, United States of America

Emily V. Sabath

Affiliation PsychoGenics Inc., Tarrytown, New York, United States of America

Vadim Alexandrov

Affiliation PsychoGenics Inc., Tarrytown, New York, United States of America

Dani Brunner

Affiliations PsychoGenics Inc., Tarrytown, New York, United States of America, Department of Psychiatry, Columbia University, New York, New York, United States of America

Emer Leahy

Affiliation PsychoGenics Inc., Tarrytown, New York, United States of America

Pascal Steiner

Affiliation Department of Neuroscience, Genentech, Inc. South San Francisco, California, United States of America

Lichuan Liu

Affiliation Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, California, United States of America

Kimberly Scearce-Levie

Affiliation Department of Neuroscience, Genentech, Inc. South San Francisco, California, United States of America

Qiang Zhou

Affiliation Department of Neuroscience, Genentech, Inc. South San Francisco, California, United States of America

Competing Interests

While conducting this study, all authors were either paid employees of Genentech, a member of the Roche Group, or employees of Psychogenics. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JH QZ PS KSL EP LL TH VA DB EL. Performed the experiments: JH QZ HL EP YHC XD EVS. Analyzed the data: JH QZ PS KSL HL EP YHC XD LL EVS TH VA DB EL. Wrote the paper: JH QZ.