About the Authors

Feng Xie

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Shunji Gao

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Juefei Wu

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

John Lof

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Stanley Radio

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Francois Vignon

Affiliation Philips Research North America, Briarcliff, New York, United States of America

William Shi

Affiliation Philips Research North America, Briarcliff, New York, United States of America

Jeffry Powers

Affiliation Philips Medical Systems Inc, Bothell, Washington, United States of America

Evan Unger

Affiliation NuvOx Pharma, Inc, Tuscan, Arizona, United States of America

E. Carr Everbach

Affiliation Swarthmore College, Swarthmore, Pennsylvania, United States of America

Jinjin Liu

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Thomas R. Porter

trporter@unmc.edu

Affiliation University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Competing Interests

TP: Lantheus Medical Imaging – Grant Support; Astellas Pharma INC. – Grant Support; Philips Research North America –Equipment Support; NuvOx Pharma INC – Supply support; GE Healthcare – Supply support. WS: Philips Research North America – Employment. FV: Philips Research North America – Employment. JP: Philips Medical Systems – Employment. EU: NuvOx Pharma INC – Owner. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FX SG JW TP. Performed the experiments: SG JW J. Lof TP. Analyzed the data: SG JW SR ECE TP. Contributed reagents/materials/analysis tools: J. Liu WS FV JP EU ECE TP. Wrote the paper: TP. Assisted with manuscript preparation: FX. Assisted with animal preparation: JW J. Lof SG.