About the Authors

Mathieu Boudes

Contributed equally to this work with: Mathieu Boudes, Pieter Uvin

mathieu.boudes@med.kuleuven.be (MB); rudi.vennekens@med.kuleuven.be (RV)

Affiliations Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Pieter Uvin

Contributed equally to this work with: Mathieu Boudes, Pieter Uvin

Affiliations Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Silvia Pinto

Affiliations Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Marc Freichel

Affiliations Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, Homburg, Germany, Pharmakologisches Institut, Universität Heidelberg, Heidelberg, Germany

Lutz Birnbaumer

Affiliation Laboratory of Neurobiology Signal Transduction, National Institute on Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United States of America

Thomas Voets

Affiliations Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Dirk De Ridder

Affiliations Laboratory of Experimental Urology, Department of Development and Regeneration, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Rudi Vennekens

Affiliations Laboratory of Ion Channel Research, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium, TRP Research Platform Leuven, Leuven, Belgium

Competing Interests

This study was partly funded by Astellas. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MB PU TV DDR RV. Performed the experiments: MB PU SP. Analyzed the data: MB PU. Contributed reagents/materials/analysis tools: MF LB. Wrote the paper: MB TV DDR RV.