About the Authors

Jia Ma

Contributed equally to this work with: Jia Ma, Qing Zhang

Affiliation Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, Anhui, China

Qing Zhang

Contributed equally to this work with: Jia Ma, Qing Zhang

Affiliation Department of Orthopedics, The Center Hospital of Bengbu, Anhui, China

Sulian Chen

Affiliation Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, Anhui, China

Binbin Fang

Affiliation Research Center of Clinical Laboratory Science, Bengbu Medical College, Bengbu, Anhui, China

Qingling Yang

Affiliation Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, Anhui, China

Changjie Chen

Affiliation Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, Anhui, China

Lucio Miele

Affiliation University of Mississippi Cancer Institute, Jackson, Mississippi, United States of America

Fazlul H. Sarkar

Affiliation Department of Pathology and Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, Michigan, United States of America

Jun Xia

zwang6@bidmc.harvard.edu (ZW); xiajunbbmc@126.com (JX)

Affiliation Department of Biochemistry and Molecular Biology, Bengbu Medical College, Bengbu, Anhui, China

Zhiwei Wang

zwang6@bidmc.harvard.edu (ZW); xiajunbbmc@126.com (JX)

Affiliations Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America, Cyrus Tang Hematology Center, Jiangsu Institute of Hematology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

Competing Interests

Co-author Dr. Sarkar is a PLOS ONE Editorial Board member. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JM ZW. Performed the experiments: JM QZ SC BF QY JX CC. Analyzed the data: JM CC ZW. Contributed reagents/materials/analysis tools: JM SC. Wrote the paper: JM LM FS ZW.