About the Authors

Simret Beraki

Affiliation Behavioral and Functional Neuroscience Laboratory, Institute for Neuro-Innovation and Translational Neurosciences, School of Medicine, Stanford, California, United States of America

Lily Litrus

Affiliation BioSeek division of DiscoverX, South San Francisco, California, United States of America

Liza Soriano

Affiliation Pacific BioDevelopment Limited Liability Company, Emeryville, California, United States of America

Marie Monbureau

Affiliation Behavioral and Functional Neuroscience Laboratory, Institute for Neuro-Innovation and Translational Neurosciences, School of Medicine, Stanford, California, United States of America

Lillian K. To

Affiliation Behavioral and Functional Neuroscience Laboratory, Institute for Neuro-Innovation and Translational Neurosciences, School of Medicine, Stanford, California, United States of America

Steven P. Braithwaite

Affiliation Circuit Therapeutics, Menlo Park, California, United States of America

Karoly Nikolich

Affiliation Circuit Therapeutics, Menlo Park, California, United States of America

Roman Urfer

Affiliation Selonterra Limited Liability Company, Belmont, California, United States of America

Donna Oksenberg

Affiliation Global Blood Therapeutics, South San Francisco, California, United States of America

Mehrdad Shamloo

mshamloo@stanford.edu

Affiliation Behavioral and Functional Neuroscience Laboratory, Institute for Neuro-Innovation and Translational Neurosciences, School of Medicine, Stanford, California, United States of America

Competing Interests

The authors list includes several individuals who are currently employed by commercial companies (Ms. Lily Litrus at BioSeek division of DiscoverX, Ms. Liza Soriano at Pacific BioDevelopment LLC, Dr. Steven Braithwaite and Dr. Karoly Nikolich at Circuit Therapeutics, Dr. Roman Urfer at Selonterra LLC, and Dr. Donna Oksenberg at Global Blood Therapeutics). Prior to current employment some of the work for the study was completed by the authors while employed at AGY Therapeutics. The team working on this program at AGY Therapeutics consisted of all the coauthors listed above. The current employers played no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript, and have no financial incentive or gain from publication. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MS. Performed the experiments: MS LL LS. Analyzed the data: MS LL LS SB MM LT. Wrote the paper: MS SB MM LT. Contributed intellectually to the work: SPB KN RU DO.