Structural and Functional Studies of FKHR-PAX3, a Reciprocal Fusion Gene of the t(2;13) Chromosomal Translocation in Alveolar Rhabdomyosarcoma

Qiande Hu; Yewen Yuan; Chiayeng Wang

doi:10.1371/journal.pone.0068065

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Peer-reviewed

Research Article

Structural and Functional Studies of FKHR-PAX3, a Reciprocal Fusion Gene of the t(2;13) Chromosomal Translocation in Alveolar Rhabdomyosarcoma

Qiande Hu ,

Contributed equally to this work with: Qiande Hu, Yewen Yuan

Affiliation Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Yewen Yuan ,

Contributed equally to this work with: Qiande Hu, Yewen Yuan

Affiliations Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, Chicago, Illinois, United States of America, Department of Oral Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Chiayeng Wang

* E-mail: chiayeng@uic.edu

Affiliations Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, Chicago, Illinois, United States of America, Department of Oral Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯

Structural and Functional Studies of FKHR-PAX3, a Reciprocal Fusion Gene of the t(2;13) Chromosomal Translocation in Alveolar Rhabdomyosarcoma

Qiande Hu,
Yewen Yuan,
Chiayeng Wang

Published: June 14, 2013
https://doi.org/10.1371/journal.pone.0068065

About the Authors

Qiande Hu

Contributed equally to this work with: Qiande Hu, Yewen Yuan

Affiliation Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, Chicago, Illinois, United States of America

Yewen Yuan

Contributed equally to this work with: Qiande Hu, Yewen Yuan

Affiliations Center for Molecular Biology of Oral Diseases, University of Illinois at Chicago, Chicago, Illinois, United States of America, Department of Oral Biology, University of Illinois at Chicago, Chicago, Illinois, United States of America

Chiayeng Wang

* E-mail: chiayeng@uic.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CW. Performed the experiments: CW QH YY. Analyzed the data: CW. Contributed reagents/materials/analysis tools: CW QH YY. Wrote the manuscript: CW. Other: Author contributions: Conceived and designed: CW. Data analysis: CW. Performed experiments: CW QH YY. Reagents/materials/analysis tools: CW QH YY. Wrote paper: CW. QH YY have equal contribution to the study described in this manuscript.

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Lung and intrathoracic tumors
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Cancers and neoplasms
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Fusion genes
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Cell differentiation
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Malignant tumors
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Renal cancer
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CAT assay
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Carcinogenesis
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