Different Regulation of Physiological and Tumor Angiogenesis in Zebrafish by Protein Kinase D1 (PKD1)

Marcus Hollenbach; Sandra Jasmin Stoll; Kristina Jörgens; Thomas Seufferlein; Jens Kroll

doi:10.1371/journal.pone.0068033

Loading metrics

Open Access

Peer-reviewed

Research Article

Different Regulation of Physiological and Tumor Angiogenesis in Zebrafish by Protein Kinase D1 (PKD1)

Marcus Hollenbach ,

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Department of Internal Medicine I, Martin Luther University Halle-Wittenberg, Halle, Germany
⨯
Sandra Jasmin Stoll ,

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany
⨯
Kristina Jörgens,

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany
⨯
Thomas Seufferlein ,

* E-mail: thomas.seufferlein@uniklinik-ulm.de

Affiliation Department of Internal Medicine I, Ulm University, Ulm, Germany
⨯
Jens Kroll

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany
⨯

Different Regulation of Physiological and Tumor Angiogenesis in Zebrafish by Protein Kinase D1 (PKD1)

Marcus Hollenbach,
Sandra Jasmin Stoll,
Kristina Jörgens,
Thomas Seufferlein,
Jens Kroll

Published: July 9, 2013
https://doi.org/10.1371/journal.pone.0068033

About the Authors

Marcus Hollenbach

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Department of Internal Medicine I, Martin Luther University Halle-Wittenberg, Halle, Germany

Sandra Jasmin Stoll

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany

Kristina Jörgens

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany

Thomas Seufferlein

* E-mail: thomas.seufferlein@uniklinik-ulm.de

Affiliation Department of Internal Medicine I, Ulm University, Ulm, Germany

Jens Kroll

Contributed equally to this work with: Marcus Hollenbach, Sandra Jasmin Stoll, Jens Kroll

Affiliations Department of Vascular Biology & Tumorangiogenesis, Center for Biomedicine and Medical Technology Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany, Division of Vascular Oncology and Metastasis, German Cancer Research Center (DKFZ-ZMBH Alliance), Heidelberg, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH SJS KJ TS JK. Performed the experiments: MH SJS KJ. Analyzed the data: MH SJS KJ TS JK. Contributed reagents/materials/analysis tools: MH SJS KJ TS JK. Wrote the paper: MH SJS TS JK.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Zebrafish
Is the Subject Area "Zebrafish" applicable to this article?

Thanks for your feedback.
Embryos
Is the Subject Area "Embryos" applicable to this article?

Thanks for your feedback.
Angiogenesis
Is the Subject Area "Angiogenesis" applicable to this article?

Thanks for your feedback.
Tumor angiogenesis
Is the Subject Area "Tumor angiogenesis" applicable to this article?

Thanks for your feedback.
Endothelial cells
Is the Subject Area "Endothelial cells" applicable to this article?

Thanks for your feedback.
Morpholino
Is the Subject Area "Morpholino" applicable to this article?

Thanks for your feedback.
Staining
Is the Subject Area "Staining" applicable to this article?

Thanks for your feedback.
SIV
Is the Subject Area "SIV" applicable to this article?

Thanks for your feedback.