About the Authors

Toshihiro Nakano

Current address: Pharmaceuticals Research Center, Asahi Kasei Pharma Corporation, Izunokuni, Shizuoka, Japan

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST), Ikoma, Nara, Japan

Izuru Ohki

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST), Ikoma, Nara, Japan

Akiho Yokota

Affiliation Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST), Ikoma, Nara, Japan

Hiroki Ashida

ashida@bs.naist.jp

Affiliations Graduate School of Biological Sciences, Nara Institute of Science and Technology (NAIST), Ikoma, Nara, Japan, Japan Science and Technology Agency (JST), Precursory Research for Embryonic Science and Technology (PRESTO), Kawaguchi, Saitama, Japan

Competing Interests

Author TN is employed by Asahi Kasei Pharma Corporation now. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: TN HA. Performed the experiments: TN IO. Analyzed the data: TN IO HA. Contributed reagents/materials/analysis tools: TN. Wrote the paper: TN AY HA.