About the Authors

Sonny C. Hsiao

Contributed equally to this work with: Sonny C. Hsiao, Hong Liu

sonny@adheren.com.

Affiliation Adheren, Inc., Berkeley, California, United States of America

Hong Liu

Contributed equally to this work with: Sonny C. Hsiao, Hong Liu

Affiliation Eureka Therapeutics, Emeryville, California, United States of America

Taylor A. Holstlaw

Affiliation Adheren, Inc., Berkeley, California, United States of America

Cheng Liu

Affiliation Eureka Therapeutics, Emeryville, California, United States of America

Catherine Y. Francis

Affiliation Adheren, Inc., Berkeley, California, United States of America

Matthew B. Francis

Affiliations Department of Chemistry, University of California, Berkeley, California, United States of America, Materials Sciences Division, Lawrence Berkeley National Laboratories, Berkeley, California, United States of America

Competing Interests

SCH, TAH, and CYF are employed by Adheren, Inc. CL and HL are employed by Eureka Therapeutics. Adheren, Inc. and Eureka Therapeutics have filed patent applications on the work described here. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SCH HL CL CYF MBF. Performed the experiments: SCH TAH HL. Analyzed the data: SCH HL CL MBF. Contributed reagents/materials/analysis tools: CL MBF. Wrote the paper: SCH TAH HL CL CYF MBF.