About the Authors

Christelle Moreau

Affiliation Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

Qun Liu

Current address: New York Structural Biology Center, Brookhaven National Laboratory, Upton, New York, United States of America

Affiliation Macromolar Diffraction Facility, Cornell High Energy Synchrotron Source, Cornell University, Ithaca, New York, United States of America

Richard Graeff

Current address: Department of Physiology, University of Hong Kong, Hong Kong, China

Affiliation Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota, United States of America

Gerd K. Wagner

Current address: Institute of Pharmaceutical Science, King’s College London, London, United Kingdom

Affiliation Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

Mark P. Thomas

Affiliation Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

Joanna M. Swarbrick

Affiliation Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

Satoshi Shuto

Affiliation Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan

Hon Cheung Lee

Affiliation Department of Physiology, University of Hong Kong, Hong Kong, China

Quan Hao

Current address: Department of Physiology, University of Hong Kong, Hong Kong, China

Affiliation Macromolar Diffraction Facility, Cornell High Energy Synchrotron Source, Cornell University, Ithaca, New York, United States of America

Barry V. L. Potter

V.L.Potter@bath.ac.uk

Affiliation Wolfson Laboratory of Medicinal Chemistry, Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BVLP CM SS HCL QH. Performed the experiments: CM QL RG MPT JMS GKW. Analyzed the data: CM QL RG MPT JMS. Contributed reagents/materials/analysis tools: CM GKW SS. Wrote the paper: CM JMS BVLP. Added input to manuscript: BVLP CM SS HCL QH QL RG MPT JMS GKW.