About the Authors
- Susanne H. Sheehy
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* E-mail: susanne.sheehy@ndm.ox.ac.uk
Affiliations Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom, The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- Alexandra J. Spencer
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- Alexander D. Douglas
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- B. Kim Lee Sim
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Affiliation Sanaria Inc., Rockville, Maryland, United States of America
- Rhea J. Longley
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- Nick J. Edwards
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- Ian D. Poulton
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Affiliation Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
- Domtila Kimani
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Affiliation Centre for Geographical Medical Research (Coast), Kenya Medical Research Institute, Kilifi, Kenya
- Andrew R. Williams
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
- Nicholas A. Anagnostou
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Affiliation Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
- Rachel Roberts
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Affiliation Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
- Simon Kerridge
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Affiliation Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
- Merryn Voysey
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Affiliation Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom
- Eric R. James
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Affiliation Sanaria Inc., Rockville, Maryland, United States of America
- Peter F. Billingsley
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Affiliation Sanaria Inc., Rockville, Maryland, United States of America
- Anusha Gunasekera
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Affiliation Sanaria Inc., Rockville, Maryland, United States of America
- Alison M. Lawrie
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Affiliation Centre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Oxford, United Kingdom
- Stephen L. Hoffman
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Affiliation Sanaria Inc., Rockville, Maryland, United States of America
- Adrian V. S. Hill
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Affiliation The Jenner Institute Laboratories, University of Oxford, Oxford, United Kingdom
Competing Interests
BKLS, ERJ, PFB, AG, and SLH are employees of Sanaria Inc., which manufactures PfSPZ Challenge. Sanaria also manufactures other products in development based on aseptic, purified, cryopreserved PfSPZ, including PfSPZ Vaccine and PfSPZ-CVac. Sanaria sells parasites and mosquitoes to the research community, but none of its major products in development have been commercialized. BKLS and SLH are inventors on patents relevant to PfSPZ Challenge. None of the authors have had any consultancies relevant to this paper. This conflict of interest does not alter these authors’ adherence to all PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: SHS AJS RJL SLH AVSH. Performed the experiments: SHS AJS RJL NJE DK ARW IDP NAA. Analyzed the data: SHS AJS ADD RJL NJE MV. Contributed reagents/materials/analysis tools: ERJ BKLS PFB SLH. Wrote the paper: SHS ADD. Project Management & Quality Assurance: AL RR SK ERJ BKLS PFB AG.