About the Authors

Hao Yin

Contributed equally to this work with: Hao Yin, Soo-Young Park

Affiliations Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America, Department of Surgery, Transplant Center, Shanghai Changzheng Hospital, Shanghai, People’s Republic of China

Soo-Young Park

Contributed equally to this work with: Hao Yin, Soo-Young Park

Affiliation Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

Xiao-Jun Wang

Affiliations Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America, The Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, People’s Republic of China

Ryosuke Misawa

Affiliations Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America, Department of Cellular Transplantation, University of Miami, Coral Gables, Florida, United States of America

Eric J. Grossman

Affiliations Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America, Northwestern University Medical Center, Chicago, Illinois, United States of America

Jing Tao

Affiliations Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America, The First People’s Hospital of Yunnan Province, Kunming, People’s Republic of China

Rong Zhong

Affiliation Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America

Piotr Witkowski

Affiliation Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America

Graeme I. Bell

Affiliation Department of Medicine, The University of Chicago, Chicago, Illinois, United States of America

Anita S. Chong

achong@uchicago.edu

Affiliation Department of Surgery, The University of Chicago, Chicago, Illinois, United States of America

Competing Interests

This work was supported in part by grants from Takeda Pharmaceuticals. Pioglitazone and Alogliptin are Takeda Pharmaceuticals products. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Performed the experiments: HY SYP XJW RM EJG JT. Analyzed the data: HY SYP AC. Wrote the paper: AC GIB PW. Provided the data and confirmed the data analysis: HY SYP RM EJG JT. Screened and identified homozygous MIP-luc mice: RZ. Provided the MIP-luc mouse: GIB.