About the Authors

Liang Xie

Contributed equally to this work with: Liang Xie, Fan Xu, Shigang Liu, Yongjia Ji

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Fan Xu

Contributed equally to this work with: Liang Xie, Fan Xu, Shigang Liu, Yongjia Ji

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Shigang Liu

Contributed equally to this work with: Liang Xie, Fan Xu, Shigang Liu, Yongjia Ji

Affiliation Suzhou Xishan Zhongke Laboratory Animal Co., Ltd., Suzhou, China

Yongjia Ji

Contributed equally to this work with: Liang Xie, Fan Xu, Shigang Liu, Yongjia Ji

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Qinming Zhou

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Qingyuan Wu

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Wei Gong

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Ke Cheng

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Juan Li

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Leilei Li

Affiliation Chinese Center for Disease Control and Prevention, Beijing, China

Liang Fang

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China

Linke Zhou

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Peng Xie

xiepeng@cqmu.edu.cn

Affiliations Institute of Neuroscience, Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing, China, Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

Competing Interests

The Suzhou Xishan Zhongke Laboratory Animal Company, Ltd. (hereinafter “the Suzhou Company”) is a private (non-governmental) independent Chinese limited liability corporate entity with three operating subsidiaries: the Production Center for Laboratory Animals, the National Resource Center for Nonhuman Primates, and the Suzhou Drug Safety Evaluation & Research Center (see http://www.szxszk.com/jigou.do). One co-author, Shigang Liu, is currently employed by the Suzhou Company through its Production Center for Laboratory Animals subsidiary, but has no consulting relationship with nor any ownership interest in the Suzhou Company or its subsidiaries. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. All other co-authors have no employment, consulting, or ownership interests in the Suzhou Company or its subsidiaries. All co-authors do not share intellectual property/patent rights, nor any joint interests in products in development or marketed products with the Suzhou Company or its subsidiaries. All co-authors declare no other competing interests related to this study.

Author Contributions

Conceived and designed the experiments: LX PX. Performed the experiments: LX FX SL YJ QZ QW WG LF LZ. Analyzed the data: LX FX LL. Contributed reagents/materials/analysis tools: LX XF SL QZ. Wrote the paper: LX FX KC JL PX.