About the Authors

Ryota Shizu

Contributed equally to this work with: Ryota Shizu, Satoshi Benoki

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Satoshi Benoki

Contributed equally to this work with: Ryota Shizu, Satoshi Benoki

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Yuki Numakura

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Susumu Kodama

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Masaaki Miyata

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Yasushi Yamazoe

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Kouichi Yoshinari

yoshinari@m.tohoku.ac.jp

Affiliation Division of Drug Metabolism and Molecular Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba-ku, Sendai, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RS SB SK KY. Performed the experiments: RS SB YN SK KY. Analyzed the data: RY SB YN SK YY KY. Contributed reagents/materials/analysis tools: RS SB SK MM. Wrote the paper: RS SB SK MM YY KY.