About the Authors

Marshall J. Glesby

mag2005@med.cornell.edu

Affiliations Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America, Department of Public Health, Weill Cornell Medical College, New York, New York, United States of America

Jeanine Albu

Affiliation Department of Medicine, St. Luke's-Roosevelt Hospital Center, New York, New York, United States of America

Ya-Lin Chiu

Affiliation Department of Public Health, Weill Cornell Medical College, New York, New York, United States of America

Kirsis Ham

Affiliation Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America

Ellen Engelson

Affiliation Department of Medicine, St. Luke's-Roosevelt Hospital Center, New York, New York, United States of America

Qing He

Affiliation Department of Medicine, St. Luke's-Roosevelt Hospital Center, New York, New York, United States of America

Varalakshmi Muthukrishnan

Affiliation Department of Medicine, St. Luke's-Roosevelt Hospital Center, New York, New York, United States of America

Henry N. Ginsberg

Affiliation Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

Daniel Donovan

Affiliation Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

Jerry Ernst

Affiliation AIDS Community Research Initiative of America, New York, New York, United States of America

Martin Lesser

Affiliation Feinstein Institute for Medical Research and Hofstra North Shore-LIJ School of Medicine, Manhasset, New York, United States of America

Donald P. Kotler

Affiliation Department of Medicine, St. Luke's-Roosevelt Hospital Center, New York, New York, United States of America

Competing Interests

MG has served as a consultant to EMD Serono on two occasions, most recently in 2007. His institution (Weill Cornell Medical College) received research support from EMD Serono for a clinical trial of recombinant human growth hormone for which he was the local principal investigator from 2004–2005. DPK and EE received research support from EMD Serono to their institution (St. Luke's-Roosevelt Hospital) for a substudy of the present study (not reported herein). EE served as a consultant to Thera Technologies in 2010, which licenses tesamorelin to EMD Serono. For this study, recombinant human growth hormone and rosiglitazone, with matching placebos, were generously donated by EMD Serono and GlaxoSmithKline, respectively. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MJG JA EE HNG DD ML DPK. Performed the experiments: MJG JA KH EE DD JE. Analyzed the data: MJG Y-LC JA QH VM. Wrote the paper: MJG.