About the Authors

Claire H. den Hoedt

Affiliations Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands, Department of Nephrology, UMC Utrecht, Utrecht, The Netherlands

Michiel L. Bots

m.l.bots@umcutrecht.nl

Affiliation Julius Center for Health Sciences and Primary Care, UMC Utrecht, Utrecht, The Netherlands

Muriel P. C. Grooteman

Affiliations Department of Nephrology, VU Medical Center, Amsterdam, The Netherlands, Institute for Cardiovascular Research VU Medical Center (ICaR-VU), VU Medical Center, Amsterdam, The Netherlands

Albert H. A. Mazairac

Affiliation Department of Nephrology, UMC Utrecht, Utrecht, The Netherlands

E. Lars Penne

Affiliation Department of Nephrology, VU Medical Center, Amsterdam, The Netherlands

Neelke C. van der Weerd

Affiliation Department of Nephrology, VU Medical Center, Amsterdam, The Netherlands

Piet M. ter Wee

Affiliations Department of Nephrology, VU Medical Center, Amsterdam, The Netherlands, Institute for Cardiovascular Research VU Medical Center (ICaR-VU), VU Medical Center, Amsterdam, The Netherlands

Menso J. Nubé

Affiliations Department of Nephrology, VU Medical Center, Amsterdam, The Netherlands, Institute for Cardiovascular Research VU Medical Center (ICaR-VU), VU Medical Center, Amsterdam, The Netherlands

Renée Levesque

Affiliation Department of Nephrology, Centre Hospitalier de l’Université de Montréal, St-Luc Hospital, Montréal, Canada

Peter J. Blankestijn

Affiliation Department of Nephrology, UMC Utrecht, Utrecht, The Netherlands

Marinus A. van den Dorpel

Affiliation Department of Internal Medicine, Maasstad Hospital, Rotterdam, The Netherlands

for the CONTRAST investigators

Membership of the CONTRAST investigators is provided in Appendix S1.

Competing Interests

CH den Hoedt, ML Bots, NC van der Weerd, EL Penne and AHA Mazairac report receiving no lecture fees, no consulting support, or grant support. MPC Grooteman reports research funded by Fresenius, Gambro and Baxter. PJ Blankestijn reports research funded by Fresenius, Gambro, Roche, Amgen and Novartis, consultant fee and honoraria for lectures from Fresenius, Gambro, Solvay, Medtronic and Novartis. R Lévesque reports research funded by Amgen Canada. PM ter Wee reports research funded by Abbott, Baxter, Gambro, Fresenius and Roche; honoraria for lectures received from Amgen, Roche, Genzyme, Fresenius. MJ Nubé reports research funded by Baxter and Fresenius; honoraria for lectures received from Fresenius and Baxter. MA van den Dorpel reports research funded by Amgen. Furthermore, this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MLB MPCG PMtW MN RL PJB MAvdD. Performed the experiments: CHdH MPCG AHAM ELP NCvdW PMtW MN RL PJb MAvdD. Analyzed the data: CHdH MLB MPCG. Contributed reagents/materials/analysis tools: CHdH MLB MPCG. Wrote the paper: CHdH MLB MPCG MAvdD. Critical review of the manuscript: CHdH MLB MPCG AHAM ELP NCvdW PMtW MN RL PJb MAvdD.