About the Authors

Florence Schaffner

Current address: UMR CNRS 7213 Laboratoire de Biophotonique et Pharmacologie, Université de Strasbourg, Illkirch, France

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Naho Yokota

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Tatiana Carneiro-Lobo

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Maki Kitano

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Michael Schaffer

Affiliation Biologics Research, Janssen Research and Development, Radnor, Pennsylvania, United States of America

G. Mark Anderson

Affiliation Biologics Research, Janssen Research and Development, Radnor, Pennsylvania, United States of America

Barbara M. Mueller

Affiliation Cancer Research, Torrey Pines Institute for Molecular Studies, San Diego, California, United States of America

Charles T. Esmon

Affiliation Coagulation Biology Laboratory, Oklahoma Medical Research Foundation and Howard Hughes Medical Institute, Oklahoma City, Oklahoma, United States of America

Wolfram Ruf

ruf@scripps.edu

Affiliation Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

Competing Interests

Please note the company affiliation of Michael Schaffer and G. Mark Anderson with Janssen Research and Development. Wolfram Ruf has served as a consultant to this company with license agreements with The Scripps Research Institute. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FS WR. Performed the experiments: FS NY TCL MS MK. Analyzed the data: FS GMA BMM WR. Contributed reagents/materials/analysis tools: BMM CTE. Wrote the paper: FS WR.