The Role of Proteasome Beta Subunits in Gastrin-Mediated Transcription of Plasminogen Activator Inhibitor-2 and Regenerating Protein1

Adrian O’Hara; Alice Howarth; Andrea Varro; Rod Dimaline

doi:10.1371/journal.pone.0059913

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Open Access

Peer-reviewed

Research Article

The Role of Proteasome Beta Subunits in Gastrin-Mediated Transcription of Plasminogen Activator Inhibitor-2 and Regenerating Protein1

Adrian O’Hara,

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Alice Howarth,

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Andrea Varro,

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯
Rod Dimaline

* E-mail: r.dimaline@liv.ac.uk

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
⨯

The Role of Proteasome Beta Subunits in Gastrin-Mediated Transcription of Plasminogen Activator Inhibitor-2 and Regenerating Protein1

Adrian O’Hara,
Alice Howarth,
Andrea Varro,
Rod Dimaline

Published: March 27, 2013
https://doi.org/10.1371/journal.pone.0059913

About the Authors

Adrian O’Hara

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Alice Howarth

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Andrea Varro

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Rod Dimaline

* E-mail: r.dimaline@liv.ac.uk

Affiliation Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RD AO’H AV. Performed the experiments: AO’H AH RD. Analyzed the data: AO’H AH RD AV. Contributed reagents/materials/analysis tools: RD AV. Wrote the paper: RD AO’H AH AV.

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Gastrin
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Proteasomes
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Cytoplasmic staining
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Transfection
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Small interfering RNA
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Gene expression
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Chromatin immunoprecipitation
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Transcriptional control
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