Enhancement of Inflammatory Protein Expression and Nuclear Factor Κb (NF-Κb) Activity by Trichostatin A (TSA) in OP9 Preadipocytes

Taiki Sato; Daisuke Kotake; Masahiro Hiratsuka; Noriyasu Hirasawa

doi:10.1371/journal.pone.0059702

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Open Access

Peer-reviewed

Research Article

Enhancement of Inflammatory Protein Expression and Nuclear Factor Κb (NF-Κb) Activity by Trichostatin A (TSA) in OP9 Preadipocytes

Taiki Sato,

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
⨯
Daisuke Kotake,

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
⨯
Masahiro Hiratsuka,

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
⨯
Noriyasu Hirasawa

* E-mail: hirasawa@m.tohoku.ac.jp

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan
⨯

Enhancement of Inflammatory Protein Expression and Nuclear Factor Κb (NF-Κb) Activity by Trichostatin A (TSA) in OP9 Preadipocytes

Taiki Sato,
Daisuke Kotake,
Masahiro Hiratsuka,
Noriyasu Hirasawa

Published: March 26, 2013
https://doi.org/10.1371/journal.pone.0059702

About the Authors

Taiki Sato

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

Daisuke Kotake

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

Masahiro Hiratsuka

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

Noriyasu Hirasawa

* E-mail: hirasawa@m.tohoku.ac.jp

Affiliation Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TS DK MH NH. Performed the experiments: TS DK. Analyzed the data: TS DK MH NH. Contributed reagents/materials/analysis tools: TS DK MH NH. Wrote the paper: TS NH.

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Transcription factors
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Inflammation
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Adipocytes
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Acetylation
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Protein expression
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DNA transcription
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Adipocyte differentiation
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Lysine
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