About the Authors

Saadet Albayrak Guralp

Affiliation Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

Yusuf E. Murgha

Affiliation Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

Jean-Marie Rouillard

Affiliations Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Mycroarray, Ann Arbor, Michigan, United States of America

Erdogan Gulari

gulari@umich.edu

Affiliation Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America

Competing Interests

The authors have the following interests. J.M. Rouillard and E. Gulari have a financial interest in Mycroarray LLC. E. Gulari is a a founder of Microarray-LLC and J.M. Rouillard is a founder and chief science officer of Microarray-LLC. The oligonucleotide library was obtained from Mycroarray-LLC. Library synthesis and 454 sequencing were performed at Mycroarray (Ann Arbor, MI). There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Implemented emulsion PCR protocol for library amplification: YEM. Conceived and designed the experiments: SAG JMR EG. Performed the experiments: SAG. Analyzed the data: SAG JMR. Contributed reagents/materials/analysis tools: JMR YEM. Wrote the paper: SAG JMR EG.