About the Authors

Teresa M. DesRochers

Affiliation Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America

Laura Suter

Affiliation F. Hoffmann La Roche, Ltd. Non-Clinical Safety, Basel, Switzerland

Adrian Roth

Affiliation F. Hoffmann La Roche, Ltd. Non-Clinical Safety, Basel, Switzerland

David L. Kaplan

david.kaplan@tufts.edu

Affiliation Department of Biomedical Engineering, Tufts University, Medford, Massachusetts, United States of America

Competing Interests

The authors have the following interests. F. Hoffmann La Roche, Ltd. partly funded this study and is the employer of Laura Suter and Adrian Roth. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: TMD LS AR DLK. Performed the experiments: TMD. Analyzed the data: TMD DLK. Contributed reagents/materials/analysis tools: TMD LS AR. Wrote the paper: TMD DLK.