RNA-Seq Reveals Activation of Both Common and Cytokine-Specific Pathways following Neutrophil Priming

Helen L. Wright; Huw B. Thomas; Robert J. Moots; Steven W. Edwards

doi:10.1371/journal.pone.0058598

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Open Access

Peer-reviewed

Research Article

RNA-Seq Reveals Activation of Both Common and Cytokine-Specific Pathways following Neutrophil Priming

Helen L. Wright ,

Contributed equally to this work with: Helen L. Wright, Huw B. Thomas

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom
⨯
Huw B. Thomas ,

Contributed equally to this work with: Helen L. Wright, Huw B. Thomas

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom
⨯
Robert J. Moots,

Affiliation Institute of Ageing and Chronic Disease, University Hospital Aintree, University of Liverpool, Liverpool, Merseyside, United Kingdom
⨯
Steven W. Edwards

* E-mail: s.w.edwards@liv.ac.uk (SWE)

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom
⨯

RNA-Seq Reveals Activation of Both Common and Cytokine-Specific Pathways following Neutrophil Priming

Helen L. Wright,
Huw B. Thomas,
Robert J. Moots,
Steven W. Edwards

Published: March 6, 2013
https://doi.org/10.1371/journal.pone.0058598

About the Authors

Helen L. Wright

Contributed equally to this work with: Helen L. Wright, Huw B. Thomas

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom

Huw B. Thomas

Contributed equally to this work with: Helen L. Wright, Huw B. Thomas

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom

Robert J. Moots

Affiliation Institute of Ageing and Chronic Disease, University Hospital Aintree, University of Liverpool, Liverpool, Merseyside, United Kingdom

Steven W. Edwards

* E-mail: s.w.edwards@liv.ac.uk (SWE)

Affiliation Institute of Integrative Biology, University of Liverpool, Liverpool, Merseyside, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HLW HBT SWE. Performed the experiments: HLW HBT. Analyzed the data: HLW HBT. Wrote the paper: HLW HBT RJM SWE.

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Neutrophils
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Gene expression
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Transcription factors
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Cytokines
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Apoptosis
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Gene regulation
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Gene ontologies
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Cytokine therapy
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