About the Authors

Patricia Dranchak

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America

Ryan MacArthur

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America

Rajarshi Guha

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America

William J. Zuercher

Affiliation Department of Chemical Biology, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America

David H. Drewry

Affiliation Department of Chemical Biology, GlaxoSmithKline, Research Triangle Park, North Carolina, United States of America

Douglas S. Auld

Current address: Center for Proteomic Chemistry, Novartis Institutes for BioMedical Research, Cambridge, Massachusetts, United States of America

Affiliation National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America

James Inglese

jinglese@mail.nih.gov

Affiliations National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland, United States of America, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

William J. Zuercher and David H. Drewry are employees of GlaxoSmithKline and this does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JI DSA PD. Performed the experiments: PD RM. Analyzed the data: PD RM RG DSA. Contributed reagents/materials/analysis tools: WJZ DHD RG. Wrote the paper: JI DSA DHD WJZ.